Formulation and evaluation of carbon nanotubes for topical drug delivery

نویسندگان

چکیده

The carbon nanotubes represent an innovative platform for controlled and targeted drug release in several biomedical applications. Carbon nanotube is one of the most efficient dispersed nano-systems with narrow size distribution ranges from 10-240 nm. possess remarkable electrical, thermal, mechanical conductivity which enables to be functionalized enhance solubility as well biocompatibility poorly bioavailable drugs. Further it can converted normal conventional system easy use such gel. purpose this study develop a stable based gel topical application fluconazole (BCS Class-II), having low high permeability improve its hence cutaneous deposition give local effect. functionalization pristine was done using PEG-400 initially. Six batches (F1-F6) loaded prepared ethanol water (2:1) tested % loading batch selected conversion (NTG1-NTG4) carbopol 934 HPMC gelling agent. Formulations were evaluated FTIR studies, loading.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation

A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...

متن کامل

Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation

A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...

متن کامل

Formulation and Evaluation of Hydrogel-Thickened Microemulsion For Topical Delivery of Minoxidil

The available minoxidil formulations for topical application suffer with major drawback and requires repeated application. The present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel-systems (MEHs) for increased percutaneous penetration of minoxidil. Minoxidil microemulsions were developed by conventional titration method using oleic-acid as oil, twe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: International Journal of Health Sciences (IJHS)

سال: 2022

ISSN: ['2550-6978', '2550-696X']

DOI: https://doi.org/10.53730/ijhs.v6ns8.9979